心理健康状况不佳作为SMuRF-不太急性心肌梗塞的风险因素和预测因素
Dimitrios V Moysidis1, Georgios Giannopoulos1, Vasileios Anastasiou2
1Third Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos 49, 54642 Thessaloniki, Greece.
心理健康状况不佳 (MHS) 在没有标准可修改危险因子 (SMuRFs) 的患者中独立预测急性心肌梗塞 (AMI). 这种不良的MHS也增加了所有AMI患者全因死亡的风险.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 在缺乏标准可修改危险因子 (SMuRFs) 的个体中,急性心肌梗塞 (AMI) 的原因尚未完全理解.
- 新出现的证据表明,心理健康状况 (MHS) 在AMI的发展和预后中起着作用.
研究的目的:
- 研究缺乏MHS和在没有SMuRFs的患者中发生AMI之间的关联.
- 评估MHS对AMI患者全因死亡率的影响.
主要方法:
- 对前性"超越SMuRFs"研究 (NCT05535582) 的分析,涉及650名AMI患者.
- 使用SF36-问卷精神部件摘要 (MCS) 评估AMI前MHS,MHS不良被定义为MCS ≤ 50.
- 应用多变量后勤和考克斯回归分析来确定没有SMuRF的AMI和全因死亡率的预测因素.
主要成果:
- 19.7%的AMI患者没有SMuRF,而44.3%的MHS很差 (MCS ≤50).
- 75%的没有SMuRF的AMI患者报告MHS不良,明显高于那些有SMuRF的患者 (36.8%).
- 糟糕的MHS (MCS ≤50) 是SMuRF-lessAMI的独立预测因素 (aOR = 0.95) 并与所有原因死亡率的增加相关 (aHR = 3.61).
结论:
- 低MHS是在没有传统风险因素的情况下发展AMI的重要独立预测因素.
- 糟糕的MHS与AMI患者因任何原因死亡的风险大大增加,无论SMuRF状态如何.
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