在SARS-CoV-2大流行期间,创伤负担影响了多发性硬化症患者
Felicita Heidler1, Michael Hecker2, Niklas Frahm2
1Department of Neurology, Ecumenic Hainich Hospital gGmbH, 99974 Mühlhausen, Germany.
Journal of clinical medicine
|April 26, 2025
概括
在8.1%的多发性硬化症 (pwMS) 患者中,COVID-19大流行引发了可能的创伤后应激障碍 (PTSD),特别是那些有先前存在的焦虑和抑郁症的人. 了解患者的特征对于有针对性的支持和对健康干预措施的明确沟通至关重要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- SARS-CoV-2 流行病对患有多发性硬化症 (pwMS) 的人群提出了独特的压力因素.
- 在疫情期间pwMS的心理影响,包括创伤和可能的创伤后应激障碍 (PTSD),仍未得到充分研究.
- 确定与创伤相关的患者特征对于提供足够的支持至关重要.
研究的目的:
- 在SARS-CoV-2大流行期间确定pwMS中可能PTSD的患病率和演变.
- 确定与pwMS中可能的PTSD相关的社会人口统计学,临床和心理因素.
- 在公共卫生危机期间为支持性护理策略和沟通提供信息.
主要方法:
- 一项双中心前性队列研究评估了149 pwMS可能的PTSD,使用适应的创伤查问卷 (TSQ) 在德国疫苗批准之前和之后.
- 对可能患有PTSD的pwMS (TSQ总分≥6) 和没有 (TSQ总分<6) 的pwMS进行比较.
- 评估包括社会人口统计数据,MS特定特征,多种药物,并发症,焦虑/抑郁水平,人格特征,负担和接种疫苗的意愿.
主要成果:
- 8.1%的pwMS患者表现出可能的PTSD.
- 可能患有PTSD的患者患有大流行前的焦虑和抑郁症的比率明显更高.
- 可能的PTSD与更高的神经症和避免伤害,更低的良心,合作力和自我指导,以及在大流行期间更大的心理/身体/社会负担有关.
结论:
- 针对性医疗和社会支持服务对于经历重大压力或创伤的人来说是必要的.
- 教育和疫苗接种策略需要明确的沟通,承认个体风险因素,并通过基于证据的信息解决问题.
- 承认pwMS的心理脆弱性是有效的公共卫生干预的关键.
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