在初级保健人群中,性别特定的多重疾病和多重行为模式
Konstantinos Spyropoulos1, Naomi J Ellis1, Christopher J Gidlow2,3
1Centre for Health and Development (CHAD), University of Staffordshire, Stoke-on-Trent ST4 2DF, UK.
概括
这项研究确定了与生活方式因素相关的8种不同的性别特异性多病症模式. 研究结果表明,在管理复杂健康状况时,以人为中心的护理需要量身定制的临床方法.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 临床流行病学临床流行病学
- 在医疗保健中的数据科学.
背景情况:
- 医疗保健正在转向理解多重疾病和多重行为是相互关联的.
- 性别差异和剂量反应关联在多病症研究中至关重要.
- 数据驱动的方法,如探索性因子分析,可以解决研究挑战.
研究的目的:
- 通过探索性因子分析来确定与性别特定的生活方式相关的多病态模式.
- 为初级保健提供者提供证据,并为未来的多病症指南提供信息.
- 探索生活方式,多病症和性别差异之间的关系.
主要方法:
- 从英国一般实践中对电子健康记录 (2015-2018) 的回顾性观察性研究.
- 包括18岁以上的生活方式多病症和多种健康风险行为患者.
- 用斜旋转进行分层探索性因子分析,以确定性别特异性的模式.
主要成果:
- 在7560名患者中,发现了8种独立的与生活方式相关的多发病模式.
- 女性:心脏代谢-神经血管 (42.97%),呼吸 (8.08%),感官损伤 (5.63%).
- 男性:心脏代谢-血管 (34.10%),生殖尿道 (9.19%),呼吸视觉 (8.20%),眼睛 (5.70%),神经血管-胃-脏 (4.54%).
结论:
- 揭示了八种与生活方式相关的多发病性性别特异性模式.
- 研究结果支持量身定制的临床方法和转向以人为中心的护理的模式转变.
- 探索性因子分析提供了具有临床价值和科学严格的多病态模式.
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