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饮食质量是否与荷兰潜在的炎症性肠病队列中的疾病活动有关?
Lola J M Koppelman1, Corien L Stevens2, Iris Barth2
1Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZG Leiden, The Netherlands.
炎症性肠病 (IBD) 患者的饮食质量与疾病活动没有明确的联系. 然而,富含动物蛋白质的饮食可能会增加活动,而方便饮食可能会减少活动,这表明IBD管理的潜在饮食改善.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 饮食流行病学 饮食流行病学
- 慢性疾病管理 慢性疾病管理
背景情况:
- 炎症性肠病 (IBD) 呈现出由饮食影响的复发缓解过程.
- 了解IBD患者的饮食质量对于管理疾病活动至关重要.
研究的目的:
- 用各种指标评估IBD患者的饮食质量.
- 调查饮食质量,饮食模式和IBD疾病活动之间的关联.
- 将IBD患者的饮食质量与荷兰普通人口进行比较.
主要方法:
- 来自荷兰两家医院的477名IBD患者的前性队列研究.
- 饮食摄入量通过特定人群的食物频率问卷 (GINQ-FFQ) 进行评估.
- 通过饮食炎症指数 (DII),地中海饮食得分 (MDS),健康饮食指标 (HDI) 和主要成分分析 (PCA) 评估饮食质量.
主要成果:
- 191名参与者完成了基线GINQ-FFQ; 53人患有活跃疾病.
- 缓解期患者报告与食物相关的生活质量 (FrQoL) 比患有活跃疾病的患者更高 (p = 0.020).
- 在整体饮食质量或特定饮食模式和IBD疾病活性之间没有发现显著的关联.
- 一个趋势表明动物蛋白质丰富的模式增加了疾病活动 (OR: 1.479,p = 0.088) 和随便饮食活动减少 (OR: 1.396,p = 0.060).
- 无论是IBD患者还是荷兰普通人口,在所有指标上都表现出饮食质量不佳的得分.
结论:
- 没有确的证据将整体饮食质量或饮食模式与IBD疾病活动联系起来.
- 潜在的关联表明,富含动物蛋白质的饮食可能与疾病活动增加有关,而方便饮食可能与活动减少有关.
- 肠胃炎症患者和荷兰一般人口的饮食质量相似,通常不佳,这表明饮食改善的余地.
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