分支链氨基酸和耐力运动中的炎症管理:分子机制和实际影响
Miaomiao Xu1,2, Danting Hu2, Xiaoguang Liu3
1School of Physical Education and Health, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Nutrients
|April 26, 2025
概括
分支链氨基酸 (BCAA) 补充剂通过促进肌肉修复和减少炎症,有助于耐力运动员. 通过激活参与肌肉蛋白质合成和能量代谢的关键分子通路,BCAA可以增强恢复和性能.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 运动科学 运动科学 运动科学
背景情况:
- 耐力运动员面临的肌肉损伤和炎症来自强烈的运动,影响恢复和表现.
- 分链氨基酸 (BCAA) 对于肌肉蛋白质合成和能量代谢至关重要.
研究的目的:
- 审查BCAA补充在肌肉修复,炎症调节和耐力运动员免疫调节中的作用.
- 探索BCAA对运动诱导的肌肉损伤和炎症影响的分子机制.
主要方法:
- 关于耐力运动员BCAA补充剂研究的文献综述.
- 对受BCAA影响的分子通路 (mTOR,AMPK,NF-κB,MAPK,JAK/STAT) 的分析.
- 检查BCAA对炎症标记物 (TNF-α,IL-6) 和肌肉损伤生物标记物 (CK,LDH) 的影响.
主要成果:
- BCAA,特别是氨酸和单氨酸,激活mTOR和AMPK通路,促进肌肉蛋白质合成和能量代谢.
- 通过调节NF-κB,MAPK和JAK/STAT通路,BCAA减轻炎症反应,降低TNF-α和IL-6水平.
- 补充BCAA可以减少肌肉疼痛,降低肌肉损伤生物标志物,改善恢复.
结论:
- 在耐力运动员中,BCAA显示出增强恢复和控制炎症的潜力.
- 需要进一步的研究来优化BCAA剂量,时间和共同补充策略,以实现个性化的协议和长期效果.
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