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从代谢角度看重症监护营养:叙述性审查
Takehiko Oami1, Akiyuki Yamamoto1, Shigenobu Ishida1
1Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Nutrients
|April 26, 2025
概括
危急疾病会导致主要的代谢变化和肠道微生物群的破坏. 针对新陈代谢和肠道微生物群的个性化营养策略可以改善恢复并减少长期影响.
科学领域:
- 关键护理医学 关键护理医学
- 人类新陈代谢的人类新陈代谢.
- 微生物组研究的研究.
背景情况:
- 危急疾病会引发显著的代谢转变,包括高代谢,胰岛素抵抗和肠道功能障碍,增加死亡率.
- 肠道微生物组及其代谢产物在关键疾病期间在调节全身炎症和免疫反应方面发挥着至关重要的作用.
研究的目的:
- 审查重症患者的代谢演变情况.
- 为了检查肠道失生症对疾病进展的影响.
- 探索调节新陈代谢和改善结果的营养策略.
主要方法:
- 在PubMed和Google Scholar的综合文献搜索到2025年2月.
- 包含了关于代谢,微生物组和危急疾病中的营养的英语文章.
- 综合相关文章以确定知识差距.
主要成果:
- 危急疾病中的代谢变化发生在几个阶段,从超能代谢到恢复.
- 肠道失调有助于系统性炎症和器官功能障碍.
- 营养干预措施,如肠道营养,益生菌和代谢学,显示出恢复肠道平衡和调节反应的潜力.
结论:
- 肠道微生物组和代谢学研究使重症患者的个性化营养成为可能.
- 量身定制的营养可以增强临床和功能恢复.
- 整合微生物组和代谢学见解可能会减轻长期严重疾病的后果.
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