肉消费是否会增加胃肠道癌症的死亡风险? 一个初步的竞争风险分析
Caterina Bonfiglio1, Rossella Tatoli1, Rossella Donghia1
1Unit of Data Science, National Institute of Gastroenterology-IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
Nutrients
|April 26, 2025
概括
高度的家禽消费 (每周超过300克) 与所有原因和胃肠道癌症 (GCs) 的死亡率增加有关. 这种风险特别高于男性,这突显了潜在的饮食健康问题.
科学领域:
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
- 胃肠病学 胃肠病学
背景情况:
- 禽肉是全球消费的一种肉类,因为它的价格实惠和可获得性.
- 高肉类消费是一个公共卫生问题,特别是在癌症和死亡风险方面.
- 研究意大利南部的饮食模式,可以了解该地区的健康状况.
研究的目的:
- 检查家禽消费与所有原因和胃肠道癌症 (GCs) 的死亡率之间的关联.
- 量化与不同水平的每周家禽摄入量相关的风险.
- 确定观察到的风险中的潜在的性别特异性差异.
主要方法:
- 一项基于人口的前性队列研究,涉及来自MICOL和NUTRIHEP队列的4869名参与者.
- 使用EPIC问卷来评估每周的肉类消费,对总肉,红肉和家禽的摄入量进行分类.
- 采用Cox比例危险回归和竞争性风险模型进行可靠的统计分析.
主要成果:
- 每周食用300克以上的家禽与食用100克以下的家禽相比,增加了27%的全因死亡风险.
- 超过300克的每周家禽消费量显示,胃肠癌 (GCs) 的风险增加了2.27倍.
- 每周食用超过300克家禽的男性面临2.61倍高的GC风险.
结论:
- 每周食用超过300克的家禽与所有原因和GCs的死亡风险显著增加有关.
- 与高家禽消费相关的死亡率和GC风险增加在男性中更为明显.
- 研究结果表明,需要制定有关家禽摄入量的饮食指南,以减轻健康风险.
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