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Updated: May 10, 2025

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
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基于生理学的生物制药对布洛芬的建模:确定关键配方参数和虚拟生物等价性评估

Javier Zarzoso-Foj1,2, Marina Cuquerella-Gilabert1,2, Matilde Merino-Sanjuan1,2

  • 1Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, 46010 Valencia, Spain.

Pharmaceutics
|April 26, 2025
PubMed
概括

基于生理学的生物制药建模 (PBBM) 确定了布洛芬颗粒表面pH值作为溶解的关键. 这使得能够定义一个体外安全空间来预测生物等价性 (BE) 和优化虚拟的BE研究.

关键词:
美国的 PBBM PBBMPBPKK PBPK 的意思是什么意思伊布罗芬是什么意思 伊布罗芬是什么意思虚拟的生物等价性

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