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基于脂质的新型配方可提高辅酶Q10的生物可用性:临床前评估和第一阶段的药物动力学试验

Andrea Fratter1,2, Alessandro Colletti2,3, Giancarlo Cravotto2,3

  • 1Department of Pharmaceutical and Pharmacological Sciences (DSFarm), University of Padova, 35129 Padua, Italy.

Pharmaceutics
|April 26, 2025
PubMed
概括

一种新的基于脂质的自化药物输送系统 (LiBADDS) 配方显著提高了辅酶Q10 (CoQ10) 的生物可用性. 这种新的方法通过利用现场乳化来改善CoQ10的吸收,从而更好地传递.

关键词:
在Caco-2中使用.生物可访问性 生物可访问性生物可用性 生物可用性辅酶Q10是一种辅酶.基于脂质的药物递送系统

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