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相关概念视频

Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
Bacterial Phylum Firmicutes01:27

Bacterial Phylum Firmicutes

Firmicutes is a diverse phylum of Gram-positive bacteria characterized by a low GC content in their genomes. This phylum includes organisms with monoderm or diderm cell envelopes, highlighting a complex evolutionary history. Firmicutes comprises several major orders, including Lactobacillales, Clostridiales, and Bacillales, which exhibit remarkable diversity in their morphology, metabolism, and ecological roles.The order Lactobacillales includes lactic acid bacteria, which are fermentative...
Bacterial Phylum Bacteroidota01:26

Bacterial Phylum Bacteroidota

The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...

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相关实验视频

Updated: Jun 27, 2026

Probiotic Studies in Neonatal Mice Using Gavage
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臭氧菌splanchnicus-A下一代益生菌候选者

Jianhong Li1,2, Jing Xu1,2, Xue Guo1,2

  • 1Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510006, China.

Microorganisms
|April 26, 2025
PubMed
概括

肠道微生物 Odoribacter splanchnicus 影响宿主的健康和新陈代谢. 它产生短链脂肪酸 (SCFA),并显示出作为代谢和炎症疾病的下一代益生菌的潜力.

关键词:
臭味菌 splanchnicuscus 是一个臭味菌.人类健康 人类健康 人类健康这是下一代益生菌.营养 营养 营养 营养

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科学领域:

  • 微生物学 微生物学
  • 肠道微生物组研究研究
  • 代谢健康 代谢健康

背景情况:

  • 臭菌splanchnicus是一种常见的肠道微生物,通过测序识别.
  • 它的丰富性与宿主健康,代谢综合征,糖尿病和肠道炎症有关.
  • O. splanchnicus可能具有双重作用,无论是保护性还是促进疾病.

研究的目的:

  • 探索O. splanchnicus在宿主新陈代谢和免疫中的作用.
  • 研究O. splanchnicus作为下一代益生菌的潜力.
  • 了解其对肠道平衡和疾病的贡献.

主要方法:

  • 高通量测序分析以检测O. splanchnicus的丰富性.
  • 对O. splanchnicus及其代谢产物的现有文献的综述.
  • 对O. splanchnicus与宿主健康标志物相关性的分析.

主要成果:

  • O. splanchnicus与各种健康状况有关,包括肥胖和炎症.
  • 它合成有益的代谢物,如短链脂肪酸 (SCFA).
  • 由O. splanchnicus产生的SCFA影响宿主能量代谢,胰岛素抵抗和免疫反应.

结论:

  • O. splanchnicus 在调节宿主新陈代谢,免疫力和肠道健康方面发挥着重要作用.
  • 它的代谢物产量,特别是SCFAs,突出了它的健康益处.
  • O. splanchnicus 是下一代益生菌和功能性食品的有希望的候选者,用于代谢和炎症性疾病.