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最近在日本的野猪和其他类动物中感染了E型肝炎病毒

Milagros Virhuez-Mendoza¹, Keita Ishijima¹, Kango Tatemoto¹

¹Department of Veterinary Science, National Institute of Infectious Diseases (NIID), Tokyo 162-8640, Japan.

|April 26, 2025

概括

肝炎E病毒 (HEV) 在日本感染野猪,检测到3b和4g亚型. 便中的传染性HEV构成来自野生动物肉的动物感染风险,强调需要监视.

科学领域:

兽医病毒学兽医病毒学
动物传播疾病动物传播疾病
公共卫生公共卫生

背景情况:

肝炎E病毒 (HEV) 是一种具有多种宿主的动物性病原体,对公众健康造成重大关注.
在日本,食用野生动物肉类,特别是野猪肉类很常见,增加了HEV传播的风险.
了解日本野生动物中的HEV流行率对于评估和减轻动物传染病风险至关重要.

研究的目的:

调查日本野猪,西卡鹿和日本血清动物中HEV的流行率和遗传多样性.
为了确定这些动物便中的病毒泄露的程度.
评估与野生动物肉类消费相关的潜在动物传播风险.

主要方法:

在1896年的血清样本中进行抗HEV抗体的血清检测.
在1034个血清样本中使用分子方法检测HEV RNA.
对473个便样本进行HEV泄漏分析.
检测到的HEV菌株的基因定型.

主要成果:

在所有七个调查县的野猪中发现了HEV抗体.
在福冈,奥伊塔,宫崎和山口县的野猪中检测到了HEV RNA.
主要的HEV亚型是3b,4a和4g,其中3b亚型显示地理聚集,4g亚型在山口长期存在.
在野猪便中证实了传染性HEV颗粒.
西卡鹿没有显示HEV感染;一个日本血清有抗体,但没有可检测的RNA.

结论:

在日本,野猪是HEV的重要储存库,有广泛感染和病毒传播的证据.
在便中检测出传染性HEV突显了环境污染和动物传播病毒的风险.
持续监测野生动物,特别是野猪,对于管理野生动物肉消费者的HEV风险至关重要.

关键词:

日本的serow是什么意思游戏肉游戏肉乙型肝炎病毒的感染.锡卡鹿是鹿的一种.野猪野猪是一种野生动物.

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