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为优化免疫疗法提供CD112受体变体的结构引导工程

Srishti Singh1, Estefania Julia2, Parismita Kalita3

  • 1Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL 33612, USA.

Molecular therapy : the journal of the American Society of Gene Therapy
|April 26, 2025
PubMed
概括

免疫检查点蛋白CD112受体 (CD112R) 抑制免疫细胞. 工程 CD112R 变种增强了对抗癌症的 T 细胞激活,证明了开发新型免疫疗法的战略.

关键词:
在CAR T细胞中,在CD112中,CD112是指CD112中,CD112是指CD112中.在CD112R中,CD112R是指CD112R.参与T细胞的参与者检查站封锁检查站封锁免疫疗法 免疫疗法蛋白质工程工程 蛋白质工程结构生物学结构生物学

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