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Updated: May 10, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Published on: December 1, 2020

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在GPCR药物发现中的深度学习:对准准确的结路径的基准测试

Luuk R Hoegen Dijkhof1,2, Teemu K E Rönkkö1,2, Hans C von Vegesack1,2

  • 1Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 160, 2100 Ø, Copenhagen, Denmark.

Briefings in bioinformatics
|April 26, 2025
PubMed
概括

深度学习模型准确地预测G蛋白合受体 (GPCR) 和激素相互作用,有助于药物发现. 与较新的模型相比,AlphaFold 2.3显示出优越的结合姿势预测.

关键词:
阿尔法折叠是什么意思阿尔法折叠在GPCR中,GPCR是指GPCR.TTATTA折叠的时间停靠的对接方式受体受体是什么 受体受体结构预测 结构预测

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