开发用于前退行症的数字健康技术
Naomi Nevler1,2, Debra Niehoff3, Amanda M Gleixner3
1Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
概括
数字健康技术 (DHT) 是追踪前退行症 (FTD) 进展的新兴工具. 开发这些技术带来了挑战,但也为新的FTD疗法提供了途径.
科学领域:
- 神经科学是一个神经科学.
- 数字健康数字健康
- 临床试验 临床试验
背景情况:
- 前变性 (FTD) 是一种罕见的神经退行性疾病,导致认知,行为,运动和语言障碍.
- 目前还没有批准的疗法可以减缓或阻止FTD的进展.
- 疾病异质性和监测挑战阻碍了临床试验的进展.
研究的目的:
- 介绍用于测量FTD发病和进展的数字健康技术 (DHT).
- 讨论为FTD开发DHT的挑战.
- 提出创建有效DHT的路线图,以帮助FTD治疗的发展.
主要方法:
- 对旨在捕捉FTD中微妙的临床损伤的新兴DHT的审查.
- 分析DHT开发人员遇到的挑战.
- 制定DHT发展的战略路线图.
主要成果:
- 许多DHT工具正在开发中,以评估FTD相关的功能域变化.
- 在为FTD创建强大可靠的DHT方面存在重大挑战.
- 一份拟议的路线图为开发适合目的的DHT提供了指导.
结论:
- 对于FTD的监测和加快治疗开发,DHT显示出有希望的结果.
- 应对发展挑战对于实现DHT在FTD中的潜力至关重要.
- 成功实施DHT可以显著有利于FTD患者护理和药物发现.
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