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相关概念视频

Dementia01:30

Dementia

65
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
65
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

317
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
317

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相关实验视频

Updated: May 10, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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开发用于前退行症的数字健康技术.

Naomi Nevler1,2, Debra Niehoff3, Amanda M Gleixner3

  • 1Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|April 26, 2025
PubMed
概括

数字健康技术 (DHT) 是追踪前退行症 (FTD) 进展的新兴工具. 开发这些技术带来了挑战,但也为新的FTD疗法提供了途径.

关键词:
痴呆症 痴呆症是一种痴呆症.诊断 诊断 诊断 诊断 诊断数字健康技术数字健康技术疾病进展和监测疾病进展和监测.前退行症 前退行症神经退行症的神经退行症

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相关实验视频

Last Updated: May 10, 2025

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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科学领域:

  • 神经科学是一个神经科学.
  • 数字健康数字健康
  • 临床试验 临床试验

背景情况:

  • 前变性 (FTD) 是一种罕见的神经退行性疾病,导致认知,行为,运动和语言障碍.
  • 目前还没有批准的疗法可以减缓或阻止FTD的进展.
  • 疾病异质性和监测挑战阻碍了临床试验的进展.

研究的目的:

  • 介绍用于测量FTD发病和进展的数字健康技术 (DHT).
  • 讨论为FTD开发DHT的挑战.
  • 提出创建有效DHT的路线图,以帮助FTD治疗的发展.

主要方法:

  • 对旨在捕捉FTD中微妙的临床损伤的新兴DHT的审查.
  • 分析DHT开发人员遇到的挑战.
  • 制定DHT发展的战略路线图.

主要成果:

  • 许多DHT工具正在开发中,以评估FTD相关的功能域变化.
  • 在为FTD创建强大可靠的DHT方面存在重大挑战.
  • 一份拟议的路线图为开发适合目的的DHT提供了指导.

结论:

  • 对于FTD的监测和加快治疗开发,DHT显示出有希望的结果.
  • 应对发展挑战对于实现DHT在FTD中的潜力至关重要.
  • 成功实施DHT可以显著有利于FTD患者护理和药物发现.