跨耳道神经刺激对糖尿病多神经病患者认知功能的影响
Moshera H Darwish1, Mohamed S El-Tamawy2, Saleh M Alhirsan3
1Department of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
概括
经耳道神经刺激 (ta-VNS) 与认知康复相结合,可显著改善糖尿病多神经病症患者的认知功能和生活质量. 这种非侵入性方法为管理这种情况提供了一个有希望的途径.
科学领域:
- 神经学 神经学
- 糖尿病学 糖尿病学
- 神经康复疗法 神经康复疗法
背景情况:
- 糖尿病多神经病与认知能力下降有关,包括执行功能,记忆力和反应时间的缺陷.
- 患有糖尿病多神经病症的患者面临患痴呆症的风险增加50%.
- 跨耳道神经刺激 (ta-VNS) 是一种新的,安全的认知增强方法.
研究的目的:
- 为了评估跨耳道神经刺激 (ta-VNS) 在改善糖尿病多神经病症患者的认知功能方面的疗效.
- 评估ta-VNS对糖尿病多神经病症患者的生活质量 (QOL) 的影响.
主要方法:
- 一项随机对照试验,涉及40名II型糖尿病多神经病症患者.
- 参与者被分配接受主动ta-VNS加计算机认知康复 (CBCR) 或假ta-VNS加CBCR3周,每周三次.
- 在基线和干预后,使用RehaCom系统和WHOQOL-BREF评估认知功能 (注意力集中,图形记忆) 和QOL.
主要成果:
- 两组都在注意力集中度和图形记忆获得时间方面表现出改善.
- 与对照组相比,研究组 (活性ta-VNS + CBCR) 在注意力集中水平,生活质量得分,图形记忆任务性能和图形记忆解决时间缩短方面表现出显著更大的改善.
- 在两组治疗后,观察到注意力集中和生活质量的显著改善,在积极刺激组的结果优越.
结论:
- 结合跨耳道神经刺激 (ta-VNS) 和基于计算机的认知康复 (CBCR),可显著增强糖尿病多神经病患者的认知功能.
- 这种综合治疗方法还可以显著改善患有糖尿病多神经病的人的生活质量.
- ta-VNS是一种有前途的辅助疗法,用于改善糖尿病多神经病的认知结果和QOL.
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