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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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阻断TIGAR可以防止CD8+ T细胞功能障碍,并引起抗AML免疫力

Jialin Cui1, Wenjie Liu2, Shiyang Zhong3,4

  • 1Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China.

Cancer immunology, immunotherapy : CII
|April 26, 2025
PubMed
概括

沉默TP53诱导的葡萄糖分解和亡调节器 (TIGAR) 增强T细胞功能,并对抗急性髓性白血病 (AML). 这种方法增强了抗白血病免疫力,并改善了小鼠模型中的生存率.

关键词:
急性髓性白血病是什么?急性髓性白血病是什么?淘汰赛小鼠 淘汰赛小鼠单细胞RNA测序的一个细胞.这是T-淋巴细胞.TP53诱导的糖解和亡调节器

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