相关实验视频

Updated: May 10, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

13.9K

双核的DNA/BSA结合亲和性和细胞毒性 (II) 复合物与氨基酸作为配体的氨基酸

Stefan Jakovljevic1,2, Petar Canovic3, Marko Spasic1,2

  • 1Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Svetozar Markovic Street 69, 34000 Kragujevac, Serbia.

Molecules (Basel, Switzerland)
|April 26, 2025
PubMed
概括

双核 (II) 复合物显示出作为抗癌剂的潜力. 基于 metionin 的复合物 Pd3 通过诱导亡,对癌细胞表现出显著的细胞毒性,而 Pd1 和 Pd2 则更有效地与 DNA 结合.

关键词:
它们是DNA DNA DNA DNA.专辑蛋白 (albumin) 是一种氨基酸是氨基酸中的一种.灭症 (apoptosis) 是一种死亡的过程.细胞毒性 细胞毒性帕拉是一种.皮拉辛 (Pyrazine) 是一种酸盐.

更多相关视频

Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII08:26

Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII

Published on: August 31, 2018

6.8K
Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer12:23

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer

Published on: August 20, 2012

14.4K

相关概念视频

The Equilibrium Binding Constant and Binding Strength02:18

The Equilibrium Binding Constant and Binding Strength

The equilibrium binding constant (Kb) quantifies the strength of a protein-ligand interaction. Kb can be calculated as follows when the reaction is at equilibrium:
12.7K
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
12.6K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.7K