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Updated: May 23, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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设计新型的三酸 (III) 复合物,包括功能化的西醇配体,通过向线粒体来改善抗癌活性

Qin Zhou1, Xiao-Bin Zhang2, An-Li Liu1

  • 1Key Laboratory of Electrochemical Energy Storage and Light Energy Conversion Matreials of Haikou City, Key Laboratory of Electrochemical Energy Storage and Energy Conversion of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China; Engineering Research Center for Hainan Bio-Smart Materials and Bio-Medical Devices, Key Laboratory of Hainan Functional Materials and Molecular Imaging, College of Emergency and Trauma, Hainan Medical University, Haikou 571199, China.

Bioorganic chemistry
|April 26, 2025
PubMed
概括

新的器官-抗癌剂,特别是复合物Ir2,通过积聚在线粒体中并诱导亡,显示出强大的抗瘤活性. 这种 (III) 复合物在抑制瘤生长方面表现出比思丁更高的疗效.

关键词:
这是一种抗癌药物.佐提亚 (Benzothiazole) 是一种一种(III) 复合物 (III) 复合物线粒体中的线粒体.三酸连接体的三酸连接体

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