青春期早期的负面生活事件与对情绪刺激的神经失活有关
Mizan Gaillard1, Scott A Jones2, Dakota Kliamovich2
1Department of Behavioral and Systems Neuroscience, Oregon Health & Science University, Portland, OR, USA; Center for Mental Health and Innovation, Oregon Health & Science University, Portland, OR, USA.
Brain and cognition
|April 26, 2025
概括
负面的生活事件会影响青少年的大脑发育,特别是在情绪处理过程中. 这些经历与大脑激活模式的改变有关,特别是在与情绪相关的区域.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 认知科学 认知科学
背景情况:
- 负面生活事件 (NLE) 与青少年心理健康问题和神经发育变化有关.
- 情绪调节和工作记忆对于处理NLEs至关重要,并且在神经生物学上相互作用.
- 青春期是精神病理发病和大脑成熟的关键时期.
研究的目的:
- 调查NLEs对青少年在情绪和工作记忆任务期间大脑激活的影响.
- 检查NLEs,情绪调节和工作记忆神经相关之间的关系.
主要方法:
- 使用功能磁共振成像 (fMRI) 进行情绪 n-back 任务.
- 分析了2150名青少年参与青少年大脑认知发展 (ABCD) 研究的数据.
- 与边缘和额头区域的大脑激活模式相关联NLEs的发生率.
主要成果:
- 较高的NLEs与桃体激活减少和与情绪相关的其他大脑区域激活增加相关,但仅在情绪处理期间.
- 在主要样本中,NLEs与任务执行之间没有显著的关联.
- 排除性分析显示,NLEs与整体任务绩效之间存在负面关联.
结论:
- 青春期早期NLEs的神经效应可能是特定于背景的,主要影响涉及情绪处理的大脑区域.
- 行为发现与先前的研究一致,但神经成像结果表明NLEs对青少年大脑功能的微妙影响.
- 这项研究强调了在研究青少年不良经历的神经生物学影响时考虑情感背景的重要性.
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