在老年人中,鼻腔手术与嗅觉功能的关联
Khamis T Suleiman1, Richard G Chiu1, Sharmilee M Nyenhuis2
1Department of Otolaryngology-Head and Neck Surgery, University of Illinois at Chicago, 1855 West Taylor St, MC 648, Room 3.87, Chicago, IL 60611, USA.
American journal of otolaryngology
|April 26, 2025
概括
在老年人中,鼻腔手术没有显著影响嗅觉功能. 这项研究在考虑其他健康因素后,没有发现先前鼻子手术和嗅觉功能障碍 (OD) 之间的关联.
科学领域:
- 老年学是指老年学的学科.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
背景情况:
- 嗅觉功能障碍 (OD) 在老年人中很常见,受年龄和神经退行等因素的影响.
- 鼻腔手术对嗅觉功能的影响尚不清楚.
- 这项研究探讨了先前的鼻腔手术和OD之间的关系.
研究的目的:
- 为了确定先前的鼻腔手术是否与老年人嗅觉功能障碍有关.
- 分析鼻腔手术对嗅觉功能的影响,使用具有全国代表性的数据集.
主要方法:
- 来自国家社会生活,健康和衰老项目 (NSHAP) 的2285名美国老年人的横截面分析.
- 嗅觉功能使用5项嗅探棒测试 (≥4个气味=正常;0-3个气味=OD) 进行评估.
- 多变量逻辑回归用于评估先前鼻腔手术和OD之间的关联,并计算了调整后的几率比率 (OR).
主要成果:
- 嗅觉功能障碍 (OD) 在18.4%的研究人口中存在.
- 虽然9.8%的OD成年人先前进行过鼻腔手术,而正常嗅觉的8.1%,但这种差异在统计学上并不显著.
- 经过调整的分析显示,先前的鼻腔手术和OD之间没有显著的关联 (OR:1.14;95%CI:0.77-1.70).
结论:
- 之前的鼻腔手术没有发现与老年人嗅觉功能障碍有显著的关联.
- 该研究强调需要进一步研究详细的外科信息,以充分理解鼻腔手术与OD的关系.
- 局限性包括在使用的数据集中缺乏特定的鼻腔手术细节.
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