绿色合成,表征,结构,形态,抗菌和细胞毒性评价的氧化纳米颗粒使用Fioria vitifolia提取物
A Nandhini1, P Anilkumar1, J Jasmin1
1Department of Chemistry, KPR Institute of Engineering and Technology, Coimbatore, Tamilnadu 641 407, India.
Biophysical chemistry
|April 26, 2025
概括
绿色合成的氧化 (ZnO) 纳米颗粒显示出强大的抗微生物和抗癌特性. 这种环保的方法为开发针对耐药细菌和癌症的新疗法提供了一个可持续的替代方案.
科学领域:
- 纳米技术 纳米技术
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
背景情况:
- 抗菌素耐药性增加需要新的治疗策略.
- 氧化 (ZnO) 纳米粒子由于其独特的特性,在癌症治疗和诊断方面具有潜力.
- 需要可持续和有效的药物输送系统和分子.
研究的目的:
- 为了绿色合成氧化 (ZnO) 纳米颗粒,使用"Fioria vitifolia"树叶提取物.
- 为了描述合成的ZnO纳米粒子.
- 评估生物合成的ZnO纳米颗粒的抗微生物和抗癌潜力.
主要方法:
- 绿色合成ZnO纳米颗粒使用植物提取物和聚烯 (PVP).
- 通过XRD,FESEM,EDX,TEM,FTIR,DRS和PL光谱进行表征.
- 对抗细菌菌株的抗微生物活性和对A549肺癌细胞和L929正常细胞的细胞毒性的评估.
主要成果:
- 通过表征技术证实了稳定的ZnO纳米颗粒的成功绿色合成.
- 显示出显著的抗微生物活性,特别是针对"Enterobacter".
- 对L929细胞具有低毒性,对A549肺癌细胞表现出强烈的细胞毒性作用.
结论:
- 生物合成的ZnO纳米颗粒具有显著的抗微生物和抗癌特性.
- 环保合成方法为传统化学合成提供了一个可持续的替代方案.
- 这些纳米颗粒显示出作为治疗感染和癌症治疗的治疗剂的双重承诺.
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