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ptophenolide通过破坏肠道的生物功能来加剧ptolide诱导的肝损伤

Binbin Zhang1, Qiuxia Lin1, Manyun Dai1

  • 1Department of Pharmacy, Laboratory of Hepatointestinal Diseases and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China.

Toxicology and applied pharmacology
|April 26, 2025
PubMed
概括

(Tripterygium wilfordii) (TW) 的三 (TP) 和三 (TPH) 的成分会导致严重的肝损伤. 通过通过代谢物PCS调解的增加肠道透性和LPS水平,TPH会加剧TP诱导的肝损伤.

关键词:
我们的肠道微生物群.肠道出血 肠道出血肝脏损伤 肝脏损伤是什么?这种植物是Tripterygium wilfordii.三托利德是一种三托利德.三烯化物 (Triptophenolide) 是一种三烯化物.

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