相关实验视频

Updated: May 14, 2025

Murine Skin Transplantation
06:42

Murine Skin Transplantation

Published on: January 16, 2008

22.4K

人类1型常规树突细胞有助于皮肤移植排斥

Thiago J Borges1, Catherine A A Lee2, Kyla Mucciarone2

  • 1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|April 26, 2025
PubMed
概括

1型常规树突细胞 (cDC1s) 是人类皮肤移植排斥的关键驱动因素. 在移植中调节这些CD141+cDC1显示出改善移植结果的前景.

关键词:
树突细胞是一种树突细胞.免疫调节的免疫调节皮肤 皮肤 皮肤血管化的复合体全移植.

更多相关视频

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice06:48

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice

Published on: July 25, 2014

12.4K
Murine Full-thickness Skin Transplantation07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

19.9K

相关概念视频

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
66.1K
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
280
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
350
T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
638
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
548