声心图左心室合指数和左心室度指数的正常值,反映左心室透气功能:一个多中心研究
Tian-Xin Dong1, Shi-Wen Li1, Xiao-Fang Pan2
1Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, No. 155 Nanjingbei Street, Heping District, Shenyang 110001, China.
概括
在健康成年人中,建立了左心室合指数 (LACI) 和左心室度指数 (LASI) 的新参考值. 这些心脏功能指标因年龄和性别而异,受血压和体重等因素的影响.
科学领域:
- 心脏病学 心脏病学
- 心脏生理学 心脏生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 左心室合指数 (LACI) 和左心室硬度指数 (LASI) 在评估左心室 (LV) 透缩功能方面表现有前途.
- 缺乏确定的参考范围阻碍了LACI和LASI的临床应用.
- 这项研究旨在确定LACI和LASI的正常参考值.
研究的目的:
- 为LACI和LASI建立性别和年龄分层的正常参考范围.
- 确定影响LACI和LASI的因素.
- 探索LACI和LASI在早期发现心脏功能障碍方面的潜力.
主要方法:
- 分析了来自55个中心的1,648名健康参与者.
- 计算LACI是最小左心室 (LA) 体积与LV终端透气体积的比率.
- 通过平均E/e'与LA储应变的比率来确定LASI.
主要成果:
- 在男女中,LACI和LASI都随着年龄的增长而增加;LACI在女性中更高.
- 对于LACI的独立预测因素包括年龄,性别,LV全球纵向菌株 (GLS) 和LA储菌株.
- 年龄,BMI,LV GLS和LA体积指数与LASI相关;参与者患有高血压正常,超重状态和不确定的LV扩张功能.
结论:
- 已经成功地确定了LACI和LASI的性别和年龄特定的参考值.
- 在解释LACI和LASI时,LV GLS,LA储菌株和LA体积指数是重要的考虑因素.
- LACI和LASI可以作为识别早期心脏功能障碍的有价值指标,特别是在高血压,肥胖和LV扩张功能障碍的背景下.
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