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循环瘤细胞隔离和丰富技术

Youbin Zhang1, David Scholten2, Wenan Qiang3

  • 1Circulating Tumor Cell Core, Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, United States; Hematology & Oncology Division, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.

International review of cell and molecular biology
|April 26, 2025
PubMed
概括

通过液体活检检测到的循环瘤细胞 (CTC) 是监测癌症进展和治疗反应的强大工具. 对CTC进行先进的多原子分析对于理解癌症生物学和改进精准医学至关重要.

关键词:
乳腺癌 乳腺癌 乳腺癌中央交易系统隔离细胞搜索 细胞搜索循环瘤细胞循环瘤细胞

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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