通过调节自,PKM2调节化疗敏感性,并预测胰腺癌的预后和免疫力

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Haosheng Zheng1,2, Jian Tan1,2, Fei Qin1,2

  • 1Department of Thoracic Surgery, Thoracic Cancer Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, Guangdong, China.

Scientific reports
|April 26, 2025
PubMed
概括

酸盐激酶M2 (PKM2) 在大多数癌症中被上调,与预后不佳相关,并影响瘤生长,免疫反应和化疗抵抗. 沉默PKM2通过调节自增强了对化疗的敏感性.

关键词:
化疗 化疗是一种化学疗法.免疫细胞的透.免疫治疗是一种免疫疗法.PKM2;预后情况胰腺癌是一种癌症.瘤微环境是一个微环境.

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