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大规模,次大规模和非大规模儿科肺栓塞的流行病学和管理:系统性审查
Mohammed Alsabri1,2, Dina Essam Abo-Elnour3, Mohammed Ayyad4,5
1Emergency Department, Al-thawara Modern General Hospital, Sana'a, Yemen. Alsabri5000@gmail.com.
这一系统性审查强调,儿童肺栓塞 (PE) 诊断和管理因严重程度而异. 早期诊断和量身定制的治疗对于改善PE儿童和青少年的治疗结果至关重要.
科学领域:
- 儿科医学 儿科医学
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
背景情况:
- 儿科肺栓塞 (PE) 是一种具有多种表现的危急疾病.
- 了解诊断,管理和结果对于这个人群至关重要.
研究的目的:
- 系统地审查有关儿科PE诊断,管理和结果的证据.
- 通过大规模,亚大规模和非大规模的严重程度分类来分析演示.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在主要数据库 (PubMed,Scopus,Web of Science,Cochrane) 进行搜索,直到2024年2月.
- 包括对21岁以下患者确认PE的研究;使用NIH工具评估偏差风险.
主要成果:
- 分析了6项涉及258名儿科患者 (平均年龄14.1岁,主要是女性) 的研究.
- 常见的危险因素:肥胖,口服避孕药,血栓,自身免疫性疾病.
- CTPA最常见的诊断工具;结果与PE严重程度相关,大规模PE的死亡率更高.
结论:
- 儿科PE需要个性化的风险分层和管理.
- 诊断延迟和严重的表现增加了发病率和死亡率.
- 未来的研究应该标准化分类,探索新的诊断方法,并比较治疗干预措施.
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