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怀孕期间大肠杆菌感染与母胎结局之间的相关性:回顾性分析

Dongdong Shi¹, Chang Liu¹, Yan Cheng¹

¹Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200082, China.

BMC infectious diseases

|April 26, 2025

概括

孕妇中大肠杆菌感染与早产和胎儿痛苦等不良结果有关. 原发性和较高的BMI是怀孕期间大肠杆菌感染的关键风险因素.

科学领域:

产科和妇科产科和妇科
传染性疾病传染性疾病
孕产妇和胎儿医学孕产妇和胎儿医学

背景情况:

怀孕期间大肠杆菌 (大肠杆菌) 感染对母亲和胎儿的健康构成重大风险.
关于大肠杆菌感染对怀孕结果的具体影响的知识有限.
这项研究解决了了解孕妇中大肠杆菌的风险因素和后果的需要.

研究的目的:

确定与孕妇大肠杆菌感染相关的高风险因素.
调查与怀孕期间大肠杆菌感染相关的孕产妇和胎儿结局.
提供关于在产科护理中管理大肠杆菌感染的见解.

主要方法:

从2020年1月至2022年12月期间住院的孕妇的临床数据的回顾性分析.
纳入标准:膜早破 (PROM),可能出现早产,可能流产,发烧和微生物检测.
根据细菌培养结果将大肠杆菌和非大肠杆菌感染群分类.

主要成果:

在7,213个标本中,有925个呈阳性,其中有202个是大肠杆菌感染病例.
大肠杆菌感染的独立风险因素:初级性 (OR=2.981) 和怀孕前的BMI ≥24 kg/m2 (OR=1.149).
大肠杆菌感染与早产PROM的增加,28周前更高的流产率,更少的满期分娩和更大的胎儿痛苦相关.

结论:

大肠杆菌在孕妇中具有很高的患病率.
母亲大肠杆菌感染与高风险人群的不良妊娠结果有关.
这些发现强调了监测和管理孕妇大肠杆菌的重要性.

关键词:

埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.感染感染感染怀孕的结果怀孕的结果风险因素风险因素

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