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Updated: May 12, 2025

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
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在亨廷顿病中对基因组架构的调节

Stephanie Portillo-Ledesma1,2, Minna Hang1, Tamar Schlick1,3,4,2

  • 1Department of Chemistry, New York University, 100 Washington Square East, Silver Building, New York, New York 10003, United States.

Biochemistry
|April 27, 2025
PubMed
概括

亨廷顿病 (HD) 改变了亨廷丁 (HTT) 基因结构,使其变得不那么紧. 这种受宏H2A1影响的结构变化可能会加速突变蛋白质的产生,有助于HD诊断和治疗.

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