评估多药在接受神经外科手术的老年患者的影响:一项回顾性研究

Sarvesh Kutty^1,2, Jonathan P Funnell^1,3,4, John G Hanrahan^1,3

¹Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.

British journal of neurosurgery

|April 27, 2025

概括

多药性,定义为使用五种或以上的药物,显著增加了老年神经外科病人的住院时间和术后并发症. 药物审查对于更好的外科手术结果至关重要.

科学领域:

神经外科神经外科
老年医学老年医学
临床药房临床药房

背景情况:

多药在老年患者中很常见.
多药对神经外科结果的影响尚未得到充分证实.

研究的目的:

评估多药对接受神经外科手术的老年患者住院时间 (LOS) 和术后并发症的影响.

主要方法:

对499名65岁以上接受神经外科手术的患者进行了回顾性审查.
患者分为多药 (≥5种药物) 和非多药组.
统计分析包括千平方,费舍尔精确,曼-惠特尼U测试和后勤回归.

主要成果:

43%的患者 (218) 具有多种药物治疗.
多药组的中位数LOS较长 (6对5天,p=0.005).
多种药物增加了术后并发症 (OR 1.62,CI 1.05-2.50,p=0.02).

结论:

多药与老年神经外科患者的不良结果有关.
术后药物评估对于改善术后结果至关重要.

关键词:

年长的老人.住院时间 (LOS)神经外科神经外科多种药房多种药房术后并发症术后并发症

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