酒精导致的癌症:全球疾病负担的最新情况2021年研究研究
Pojsakorn Danpanichkul1, Yanfang Pang2,3,4,5, Luis Antonio Díaz6,7,8,9
1Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Alimentary pharmacology & therapeutics
|April 27, 2025
概括
到2021年,与酒精有关的全球癌症死亡人数增长了51%. 尽管酒精导致的癌症的年龄标准化死亡率下降,但整体死亡率增加,突显了全球紧急的卫生需求.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 全球范围内,酒精消费是癌症发展的重要危险因素.
- 了解酒精导致的癌症的负担对于公共卫生干预至关重要.
研究的目的:
- 提供全球,区域和国家对酒精导致的癌症负担的最新评估.
- 从2000年到2021年分析死亡率和年龄标准化死亡率 (ASDR) 的趋势.
主要方法:
- 全球疾病负担分析研究2021年数据.
- 对由酒精引起的癌症的死亡和ASDR的检查,按地区,国家和社会人口统计指数 (SDI) 分层.
- 计算年度百分比变化 (APC),以反映2000年至2021年之间的趋势.
主要成果:
- 在全球范围内,从2000年到2021年,由酒精引起的癌症死亡人数增加了51%,到2021年达到343,370,占所有癌症死亡人数的3.5%.
- 肝,食道和结肠直肠癌是导致酒精致癌死亡的主要原因.
- 虽然酒精导致的癌症的整体ASDR在全球范围内下降了 (APC: -0.66%),但在南亚和低和低至中等SDI国家增加了.
结论:
- 尽管ASDR在全球范围内有所下降,但由酒精引起的癌症死亡总数正在上升,区域和人口统计学差异很大.
- 胃肠道癌症特别令人担忧,同时,早期发病的唇部和口腔癌的增加.
- 迫切,有针对性的全球和区域战略是必要的,以减轻与酒精有关的癌症日益增加的负担.
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