在患有的妇女怀孕前停止使用酸的结果
Frank Vajda1, Terence O'Brien2, Janet Graham3
1Departments of Medicine and Neurosciences, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia 3050; Department of Neuroscience, Monash University, Melbourne, VIC, Australia 3004.
在怀孕之前停止使用酸可以降低患有的妇女的胎儿形风险. 然而,这可能会略微增加在怀孕期间失去控制的机会,特别是对于那些患有一般性的人来说.
科学领域:
- 神经学 神经学
- 甲状腺学 甲状腺学
- 药理学 药理学是指药理学的学科.
背景情况:
- 会影响生育年龄的女性.
- 酸是一种常见的抗药物,具有已知的致病风险.
- 在怀孕期间治疗需要平衡控制和胎儿安全.
研究的目的:
- 为了评估怀孕前的氨酸戒断对胎儿形率的影响.
- 评估怀孕前的瓦尔酸戒断对发作控制在怀孕期间患有的妇女的影响.
主要方法:
- 使用澳大利亚怀孕登记册数据进行的回顾性队列研究.
- 在怀孕前停止服用烯酸盐的妇女与继续服用烯酸盐的妇女之间的结果比较.
- 分析包括胎儿形率和整个怀孕期间的自由率.
主要成果:
- 在怀孕期间,怀孕前停止服用氨酸的孕妇中观察到明显较低的胎儿形率 (5.5%与13.0%相比).
- 在怀孕期间的发作自由率在氨酸戒断组略低 (53.9%对61.6%),但这种差异没有达到统计学意义.
- 在患有普遍性的女性中,戒断组的发作自由度降低接近统计学意义.
结论:
- 在患有的女性中,怀孕前取消氨酸治疗与胎儿形风险降低有关.
- 虽然停止服用氨酸可能会导致失去控制风险的边缘性增加,特别是在一般性中,但应考虑减少形率的好处.
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