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Updated: May 17, 2025

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人类Mn-超氧化物脱酶乙化保护免受酶化和无活化

Gianfranco Frattini1, Juan L Puzzolo1, Salvador I Drusin1

  • 1Instituto de Química Rosario (CONICET-UNR) and Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Santa Fe, Argentina.

Archives of biochemistry and biophysics
|April 27, 2025
PubMed
概括

在Lys29中对超氧化物脱酶 (MnSOD) 的乙化,通过阻碍超氧化物进入来降低其活性. 这种可逆的修改可能会保护MnSOD在细胞应激过程中免受过氧酸盐的不可逆性失活.

关键词:
乙化 乙化是一种在 MnSOD 中使用.分子动力学模拟的模拟.过氧化酸盐的过氧化超氧化物可访问性

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