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Updated: May 10, 2025

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
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发育内皮位-1通过抑制Cmpk2-cGAS-STING通路并促进修复性巨细胞过渡来促进肠道炎症的解决

Meihui Tao1, Li Wang2, Chaoyue Chen3

  • 1Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Journal of advanced research
|April 27, 2025
PubMed
概括

发育性内皮位1 (DEL-1) 通过抑制Cmpk2-cGAS-STING通路并促进巨细胞修复,减少IBD中的肠炎症. 这一发现将DEL-1定位为炎症性肠病 (IBD) 的潜在治疗方法.

关键词:
在Cmpk2-cGAS-STING路径中.德尔-1 是一个DEL-1.炎症性肠病是一种炎症性肠病.这是修复性巨细胞.转录因子Spi1

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