基因变异类型和位置与一般人口乳腺癌风险的关联

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Updated: May 10, 2025

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M P Akamandisa1, N J Boddicker2, S Yadav3

  • 1Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Annals of oncology : official journal of the European Society for Medical Oncology
|April 27, 2025
PubMed
概括

在BRCA2外因子11的致病变体 (PVs) 与较低的乳腺癌风险和晚期诊断有关. 在ATM,BRCA1,CHEK2和PALB2中的其他BRCA2变异和PV显示了不同的风险概况.

关键词:
乳腺癌的风险 乳腺癌的风险致病变体的类型和位置.基于人口的队列队列.

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