相关实验视频
Updated: May 10, 2025

09:15
In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
333
在COVID-19住院后发生静脉血栓栓塞:COVID中的静脉血栓虚拟监测) 研究
Deborah M Siegal1, Marie-Pier Arsenault2, Jameel Abdulrehman3
1Department of Medicine, University of Ottawa, Ottawa, Canada; Ottawa Hospital Research Institute, Ottawa, Canada.
Journal of thrombosis and haemostasis : JTH
|April 27, 2025
概括
在COVID-19住院后出现症状性静脉血栓栓塞 (VTE) 的风险很低,90天发生率为0.90%. 常规的出院后抗凝药可能对所有患者都没有好处.
科学领域:
- 医学研究 医学研究
- 心血管医学 心血管医学
- 传染病流行病学 传染病流行病学
背景情况:
- 众所周知,COVID-19会导致前血栓状况,增加住院患者静脉血栓栓塞 (VTE) 的风险.
- 在COVID-19出院后,VTE的发病率尚未得到充分的前性研究.
研究的目的:
- 为了调查COVID-19感染住院后患者症状性VTE的发生率.
- 评估二次结果,包括出血事件和死亡率.
主要方法:
- 未来的,多中心队列研究 (VVIRTUOSO) 涉及513名住院的COVID-19患者.
- 虚拟随访90天,监测症状,客观证实VTE.
- 排除标准包括缺乏虚拟评估能力或放出后抗凝药.
主要成果:
- 在90天后,症状性VTE的累积发病率为0.90% (95% CI,0.30%-2.18%).
- 严重出血发生在0.20%,临床相关的非重大出血发生在1.47%,死亡率发生在3.19%的参与者中.
- 411名参与者完成了90天的随访.
结论:
- 在COVID-19住院后,症状性VTE发生率较低.
- 研究结果表明,常规的出院后药理性血栓预防可能不会为未被选择的患者提供整体临床益处.
- 进一步的研究可能会完善退院后VTE预防的风险分层.
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