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使用MeRIP-seq/RNA-seq使用差异性重组蛋白表达的CHO细胞的m6A修饰配置文件

Wen Wang1, Hai-Tong Wang1, Yang Guo1

  • 1School of Pharmacy, XinXiang Medical University, Xinxiang 453003, Henan, China; International Joint Laboratory of Recombinant Drug Protein Expression System, Xinxiang 453003, Henan, China; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang 453003, Henan, China.

International journal of biological macromolecules
|April 27, 2025
PubMed
概括

N6-甲基氨酸 (m6A) RNA修饰调节了中国仓鼠卵巢 (CHO) 细胞中治疗性蛋白质的产生. 抑制特定的基因可以提高蛋白质产量,为细胞系优化提供策略.

关键词:
中国仓鼠卵巢 (CHO) 细胞这就是MeRIP-seqq.在RNA-seqqq.再组合蛋白质的表达方式m6A 修改的修改

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