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对比前列腺癌的活检策略:系统性审查和网络元分析

Yiqi Huang¹, Cailiu Wei², Fenjuan Chen³

¹Department of Nephrology, Shaoxing Second Hospital, Shaoxing, Zhejiang, China.

|April 27, 2025

概括

与传统方法相比,磁共振成像引导前列腺活检 (MRI-PB) 提高了前列腺癌 (PCa) 检测率. 核磁共振-认知-PB显示了强大的改善,但需要进一步比较核磁共振-PB技术.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
医疗成像医学成像
在瘤学瘤学.

背景情况:

磁共振成像引导前列腺活检 (MRI-PB) 是前列腺活检 (PB) 策略的重大进展.
现有证据需要综合来比较和排名各种PB技术以进行最佳前列腺癌 (PCa) 诊断.

研究的目的:

为了比较和排名不同的前列腺活检策略,专注于MRI引导的方法.
提供关于PB选项在前列腺癌诊断中的有效性的最新证据.

主要方法:

系统审查和随机对照试验 (RCT) 的元分析发表至2024年12月.
搜索了包括PubMed,Cochrane Library Central,Scopus和Embase在内的主要数据库.
包括24个RCT评估11个不同的PB策略.

主要成果:

与标准TRUS(10-12)-PB相比,MRI-认知-PB和MRI/TRUS-PB显著改善了先前负面活检的患者的PCa总体检测率.
与TRUS10-12)-PB相比,MRI/TRUS-PB在前列腺体体积≤50mm3的PCa检测方面表现出更高的疗效.
MRI-cognitive-PB在检测临床显著性 (csPCa) 或临床重要性 (ciPCa) 前列腺癌方面没有显著的优势.

结论:

核磁共振-认知-PB提供了改善的整体PCa检测率与TRUS(10-12)-PB相比,但缺乏对csPCa和ciPCa检测的优越性.
在较小的前列腺中,MRI/TRUS-PB对PCa检测有效.
进一步对不同MRI-PB技术进行对比,对于完善诊断策略至关重要.

关键词:

活检是为了检查生物质.网络元分析网络元分析前列腺癌是什么意思前列腺癌是什么意思

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