在加拿大北克的COVID-19大流行期间药物使用趋势,加拿大
Maude Gosselin1, Marjolaine Dubé1, Marc Simard1,2,3
1Institut national de santé publique du Québec, Quebec, Canada.
Scientific reports
|April 27, 2025
概括
在加拿大北克,COVID-19大流行改变了药物的使用,新处方的初始下降,随后一些慢性疾病的增加. 公共卫生规划必须考虑到这些转变.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- COVID-19 疫情对全球卫生服务和个人健康行为产生了重大影响.
- 了解药物使用的变化对于评估医疗保健系统压力和患者结果至关重要.
研究的目的:
- 在COVID-19大流行期间,分析加拿大北克省药物使用模式的变化.
- 将观察到的药物使用与不同流行病波的流行前期望进行比较.
主要方法:
- 利用一个大规模的医疗保健数据库,包含超过300万个受北克公共药物计划 (2016年1月至2022年3月) 覆盖的个人.
- 采用了近比松回归模型来估计预期的每周药物使用量.
- 计算了四个大流行时期的流行和新药使用者的观察到预期的比率.
主要成果:
- 大多数药物开始在第一波期间下降,抗精神病药物显示轻微增加.
- 从第二波开始,抗糖尿病,降脂和ADHD药物使用率超过了预期.
- 系统性抗生素和用于阻塞性肺部疾病的药物的使用仍然低于预期水平,特别是在后一波.
结论:
- 随着COVID-19大流行,药物使用发生了重大,多样化的变化,影响了新处方和慢性药物管理.
- 从预期的药物使用模式观察到的偏差需要在研究和公共卫生准备中考虑未来的流行病.
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