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Updated: May 3, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
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The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli

Published on: January 13, 2013

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解读低素B生物合成途径和D-最佳设计,以优化生产

Muath Suliman1, Amr S Bishr2, Khaled M Aboshanab3,4

  • 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, 9088, Abha, Saudi Arabia.

World journal of microbiology & biotechnology
|April 27, 2025
PubMed
概括

这项研究通过优化Streptomyces hygroscopicus培养条件来优化Hygromycin B (HYG-B) 生产. 使用D-最佳设计的统计优化显著增加了HYG-B的产量,为工业应用铺平了道路.

关键词:
S. hygroscopicus NRRL ISP-5578 这种病毒的确存在.2 - 德克索斯特雷普坦胺 - 氨基糖化.D-最佳设计的设计.希格罗米辛B是一种药物.响应表面方法 (RSM)

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