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帕金森病中的冷漠:在一个队列表征研究中探索的诊断难题

Adrianna M Ratajska¹, Katie Rodriguez¹, Hannah Appleton¹

¹Department of Clinical and Health Psychology (Ratajska, Rodriguez, Appleton, Schade, Gertler, Kenney, Bowers) and Department of Neurology, Norman Fixel Institute for Neurological Diseases (Pontone, Bowers), University of Florida, Gainesville.

The Journal of neuropsychiatry and clinical neurosciences

|April 28, 2025

概括

帕金森病 (PD) 中的冷漠往往没有被诊断出来. 超过一半的纯无动于衷的PD患者没有接受精神病学诊断,这表明这些人的临床护理存在重大差距.

科学领域:

神经精神病学是一种神经精神病学.
运动障碍运动障碍
精神病诊断精神病诊断精神病诊断

背景情况:

漠不关心是帕金森病 (PD) 中常见的一种神经精神症状,与抑郁症不同.
它显著影响PD患者的日常功能和生活质量.
目前的诊断标准,如DSM-5,不承认冷漠作为一个独立的诊断.

研究的目的:

调查精神病医生如何诊断显著冷漠的帕金森病患者.
在临床环境中检查诊断分类对"纯无动于衷"个体的诊断分类.

主要方法:

确定了55名帕金森病患者的"纯无动于衷" (高无动于衷,低抑郁/焦虑得分).
这些患者接受了标准的精神病学评估,使用DSM-5标准.
精神病医生被蒙蔽了对自我报告无动于衷,抑郁和焦虑等级的结果.

主要成果:

超过一半 (53%) 的"纯无动于衷"组没有接受精神病诊断.
其余患者被诊断为焦虑症 (27%),抑郁症 (5%) 或其他精神疾病 (9%).
常见的诊断包括未指明的焦虑/抑郁障碍和泛性焦虑障碍.

结论:

帕金森病中精神疾病的诊断缺口很大,特别是无动于衷.
超过50%的无动于衷的PD患者缺乏诊断可能导致未满足的临床需求.
这凸显了对帕金森病无动于衷的诊断框架的改进的需要.

关键词:

漠不关心漠不关心抑郁症抑郁症抑郁症情绪障碍情绪障碍情绪障碍帕金森氏症帕金森氏症

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