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Updated: May 10, 2025

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谷氨酸中的GLS1媒介冗余性通过激活NMDAR/Ca2+/β-Catenin通路加速动脉化

Ziting Zhou1, Bing Dong1, Dayu He1

  • 1Department of Cardiology, Joint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic Diseases, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, 518033, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|April 28, 2025
PubMed
概括

谷氨酸酶1 (GLS1) 活性会提高谷氨酸水平,在慢性病 (CKD) 患者中促进动脉化. 抑制GLS1或谷氨酸通过阻断特定的细胞信号通路来减少化.

关键词:
在 GLS1 中使用.没有NMDAR,没有NMDAR.动脉化是一种动脉化.谷氨酸酸盐的使用方法骨质性重编程是一种骨质性重编程.这是β-Catenin.

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