脱水和营养不良-相似但不同:来自老年住院患者前性观察研究的数据
Nina Rosa Neuendorff1, Rainer Wirth1, Kiril Stoev1
1Department of Geriatrics, Marien Hospital Herne, University Hospital, Ruhr University Bochum, 44625 Herne, Germany.
Nutrients
|April 28, 2025
概括
营养不良和脱水在老年人中很常见,但很少同时发生. 较高的BMI和肌素预测脱水风险,需要在住院患者中对这些情况进行单独的查.
科学领域:
- 老年医学 老年医学
- 临床营养学 临床营养学
- 内部医学 内部医学
背景情况:
- 脱水和营养不良在老年人中很普遍,共享诸如失水症和痴呆症等危险因素.
- 关于这种人群中营养不良和脱水的同时发生的数据有限.
- 在一个多中心前性试验中进行了探索性分析,重点是营养不良的决定因素.
研究的目的:
- 评估老年住院患者营养不良和脱水之间的潜在关联.
- 确定共同的风险因素和共同发生的模式.
- 为了告知临床实践关于这些条件的评估.
主要方法:
- 对454名住院的老年人进行了全面的老年医学评估.
- 使用全球营养不良领导倡议 (GLIM) 标准和MNA-SF.标准评估营养状况.
- 通过计算血清度来确定脱水;分析了常规实验室测试,包括肌素.
主要成果:
- 营养不良的发生率为45% (MNA-SF) 和42% (GLIM). 脱水发生在32%的患者身上.
- 血清肌素升高和更高的体重指数 (BMI) 是脱水的重要预测因素.
- 观察到13%的重叠;营养不良和脱水之间没有发现显著的关联 (p = 0.903).
结论:
- 营养不良和脱水是常见的,但不经常在住院的老年人同时发生.
- 体重指数和肌素水平是这群人群脱水风险的关键预测指标.
- 建议对营养不良和脱水进行单独的查,以有效的个人管理.
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