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Mousumi Bose¹, Nancy L von Thun¹, Adrian L Kerrihard¹

¹Department of Nutrition and Food Studies, College for Community Health, Montclair State University, Montclair, NJ 07043, USA.

|April 28, 2025

概括

对于Zellweger谱系障碍 (ZSD) 患者,使用护理人员的输入,对饮食的评估是可行的. 营养摄入量通常符合要求,除了纤维,不管养方法.

科学领域:

生物化学生物化学
遗传学是一个遗传学.
营养科学营养科学

背景情况:

泽尔韦格谱系障碍 (ZSD) 是一种罕见的遗传疾病,影响过氧体生物发生.
ZSD会导致多器官功能障碍,影响生长,导致食困难.
之前没有任何研究评估了ZSD患者的饮食摄入量.

研究的目的:

评估患有ZSD或相关过氧体疾病的个体的营养摄入量.
为了比较两种饮食评估方法:24小时的回忆和3天的食物记录.
用家庭护理人员的意见来评估饮食评估的可行性.

主要方法:

与家庭护理人员一起进行了多次24小时的饮食召回.
照顾者还在六个月内为他们的孩子完成了为期3天的食物记录.
从21名受试者 (1-33岁) 收集了数据,包括口服和肠道食的个体.

主要成果:

饮食回忆和3天食物记录显示了营养摄入的高相关性 (r2 = 0.998,p < 0.0001).
平均营养摄入量通常达到或超过饮食参考摄入量 (DRI).
大多数受试者的纤维摄入量约为DRI的50%.

结论:

在ZSD中对饮食的评估是可行的,使用护理人员的输入,无论养方式如何.
通过使用不同的评估方法,可以获得一致的饮食摄入数据.
研究结果支持这些方法对ZSD和类似遗传疾病的适用性.

关键词:

医学研究所医学研究所泽尔韦格的谱系障碍护理人员报告报告饮食记录饮食记录营养素营养素营养素营养要求营养要求过氧体乱过氧体乱罕见病是一种罕见的疾病.

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