哺乳和未来的心血管,脏和代谢健康 - - 一篇叙述性评论
You-Lin Tain1,2,3, Ying-Jui Lin4,5,6,7, Chien-Ning Hsu8,9
1Division of Pediatric Nephrology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.
Nutrients
|April 28, 2025
概括
哺乳的好处是众所周知的,但其与长期后代健康的联系尚不清楚. 本综述探讨了母乳如何重新规划健康,以预防心血管--代谢综合征 (CKMS).
科学领域:
- 生殖生物学 生殖生物学
- 发展生物学 发展生物学
- 代谢健康 代谢健康
背景情况:
- 母乳对婴儿健康的作用已经确立,但其对后代疾病风险的长期影响尚未完全理解.
- 心血管--代谢综合征 (CKMS) 是一个日益严重的全球健康问题.
- 健康和疾病的发育起源 (DOHaD) 概念将生命早期的因素,包括哺乳期,与以后的疾病风险联系起来.
研究的目的:
- 审查涉及母乳的策略,以重新编程后代的心血管,脏和代谢健康.
- 检查乳房受影响的CKMS编程背后的机制.
- 以突出使用母乳成分的潜在早期干预措施.
主要方法:
- 文献综述侧重于母乳,哺乳期和CKMS.
- 对了解CKMS编程机制的实验进步进行分析.
- 对生命早期干预的动物模型的检查.
主要成果:
- 哺乳期障碍与患CKMS的风险增加有关.
- 母乳中的营养素和生物活性成分对婴儿健康至关重要.
- 利用母乳成分的早期干预措施有望改善长期健康结果.
结论:
- 母乳在规划后代的长期健康和疾病风险方面发挥着至关重要的作用.
- 哺乳期不足可以增加CKMS发展的风险.
- 在哺乳期使用母乳的有针对性的干预措施,有可能预防CKMS,并需要进一步的研究和临床翻译.
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