乙型肝炎病毒感染和怀孕:孕期糖尿病和早产风险增加
Xiumei Cai1, Suiping Huang2, Zuliang Ma3
1Xiumei Cai, Department of Medical Quality Control, Nanhai Affiliated Maternity and Children's Hospital of, Guangzhou University of Chinese Medicine, Foshan, China.
Pakistan journal of medical sciences
|April 28, 2025
概括
孕妇感染乙型肝炎病毒 (HBV) 会增加妊娠期糖尿病,肝脏内胆固醇症和34周前早产的风险. 这突出了与HBV相关的潜在妊娠并发症.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 周围生理学 周围生理学
背景情况:
- 乙型肝炎病毒 (HBV) 感染是一个全球性的健康问题.
- 了解HBV对怀孕结果的影响对于母亲和婴儿健康至关重要.
研究的目的:
- 调查乙型肝炎表面抗原 (HBsAg) 阳性和不良妊娠结果之间的关联.
- 为了确定与HBV感染相关的特定妊娠并发症.
主要方法:
- 对13980名孕妇 (2020-2022) 的回顾性研究.
- 在HBsAg阳性 (1,059) 和HBsAg阴性 (12,921) 组之间比较妊娠结果.
主要成果:
- 具有HBsAg阳性的孕妇的妊娠糖尿病发病率明显较高 (OR,1.20).
- 在HBsAg阳性组中观察到妊娠 (OR,1.85) 和34周前早产 (OR,1.96) 肝脏内胆固醇形成的发病率增加.
- 乙型肝炎病毒感染与这些结果之间的关联在统计学上是显著的.
结论:
- 怀孕期间的乙型肝炎感染与妊娠期糖尿病,怀孕的肝脏内胆固醇症和早产的风险增加有关.
- 需要进一步的研究,以充分阐明HBV感染对怀孕的机制和影响.
- 在HBsAg阳性孕妇中,对这些并发症进行临床警是有必要的.
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