生育能力的维护:对于性别失调的年轻人来说,有没有一个模式?
Michael K Laidlaw1, Jennifer Lahl2, Angela Thompson3
1Department of Endocrinology, Diabetes, and Metabolism, Michael K. Laidlaw, MD, Inc., Rocklin, CA, United States.
Frontiers in endocrinology
|April 28, 2025
概括
保护生育能力为癌症患者和患有性别障碍的年轻人提供了希望. 需要对长期生殖健康和受孕成功进行更多的研究,以治疗性别失调症.
科学领域:
- 生殖医学 生殖医学
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 辅助生殖技术 (ART) 和冷生物学的进步有助于癌症患者面临不孕症.
- 由于青春期阻断和荷尔蒙疗法,性别障碍症 (GD) 的生育能力保护 (FP) 提出了独特的挑战.
研究的目的:
- 审查目前对青少年和青少年前期的FP的知识和伦理考虑.
- 专注于癌症治疗和性别障碍症 (GD) 的FP.
主要方法:
- 对目前关于生育保护的研究进行文献综述.
- 分析与年轻人的FP相关的伦理问题.
主要成果:
- 有限的基于证据的研究存在于GD的年轻人中的FP.
- 对于GD治疗,长期生殖健康影响和受孕成功率在很大程度上是未知的.
结论:
- 对于癌症患者和患有GD的年轻人来说,FP是一个至关重要的选择.
- 进一步的研究对于了解这些人群的长期结果和优化FP策略至关重要.
相关概念视频
Infertility in Males
153
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
153
Meiosis II
181.4K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
181.4K
Ethnic Identity within a Larger Culture
15
Adolescents from ethnic minority backgrounds face a multifaceted journey in forming their identities, shaped by the intersections of cultural expectations and personal exploration. For these adolescents, identity formation involves not only typical developmental challenges but also navigating the perceptions and attitudes of the majority culture. As they grow, adolescents in ethnic minority groups often become increasingly aware of stereotypes, social biases, and discrimination, all of which...
15
Sex-linked Disorders
98.0K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
98.0K
Socioemotional Experience and Gender Development
14
Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
14
Infertility in Females
184
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
184


