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Updated: May 10, 2025

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations
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整合多omics和实验技术来解码肝细胞癌中无处不在的蛋白质修饰

Haikun Yang1, Yuan Chen2,3, Zheng Zhou4

  • 1Department of Gastroenterology, Shanxi Provincial People's Hospital, Taiyuan, China.

Frontiers in pharmacology
|April 28, 2025
PubMed
概括

在瘤微环境 (TME) 中,乌比基化显著影响肝细胞癌 (HCC) 的进展和免疫逃逸. 该基因UBE2C被确定为HCC治疗的关键参与者和潜在的治疗标.

关键词:
在UBE2C中,UBE2C是免疫调节 免疫调节预后 预后 预后瘤细胞就是瘤细胞.瘤微环境是一个微环境.无处不在的化

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Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
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