性别差异,预后指标和肺部典型癌症的生存差异:一个SEER数据库分析分析
Asim Ahmed1, Abdul Qahar Khan Yasinzai2, Bisma Tareen3
1Medical College of Georgia, Augusta, Georgia, USA.
概括
手术为典型的癌状肺瘤,一种罕见的癌症提供了最好的预后. 老年和远距离传播等因素对这些神经内分泌瘤的存活率产生负面影响.
科学领域:
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 典型的癌类瘤是肺部罕见的神经内分泌新生瘤,占所有肺癌的不到1%.
- 这项研究调查了影响典型癌症患者生存的人口,种族和性别差异.
研究的目的:
- 评估人口特征,种族和性别差异以及瘤特征对典型癌状瘤患者的生存的影响.
- 为了确定影响典型癌性肺癌生存结果的预后因素.
主要方法:
- 利用了来自监测,流行病学和最终结果 (SEER) 数据库 (2000-2018) 的数据.
- 采用多变量考克斯回归分析,根据人口和临床因素来确定生存率.
主要成果:
- 确定了11713例典型的癌状瘤;平均年龄为61.8岁,主要影响女性 (70.1%) 和白人 (89.4%).
- 整体5年生存率为84.3%. 手术产生了最高的5年生存率 (97.2%),其次是组合疗法 (86.9%),辐射 (71.9%) 和全身疗法 (49.8%).
结论:
- 手术是典型的癌性肺瘤的主要治疗方式,提供最好的生存结果.
- 高龄 (>60岁),男性性别,远程瘤扩散和肝转移与更差的预后有关.
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