在精神分裂症中,声乐特征,精神病症状和认知功能的关联
Tomoya Natsuyama1, Enkhmurun Chibaatar1, Yuko Shibata2
1Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, 807-8555, Japan.
Neuropsychiatric disease and treatment
|April 28, 2025
概括
使用梅尔谱图和梅尔频率塞普斯特拉系数 (MFCC) 的高级语音分析显示了评估精神分裂症认知功能的潜力. 研究结果表明,声音特征与认知缺陷相关,而不是直接与精神症状相关.
科学领域:
- 神经科学是一个神经科学.
- 计算精神病学是一种计算精神病学.
- 语音处理 语音处理
背景情况:
- 精神分裂症的诊断和管理往往依赖于主观的评估.
- 客观生物标志物是早期检测和监测精神分裂症认知障碍所需的.
研究的目的:
- 调查高级计算技术在声分析中对评估精神病症状和精神分裂症认知功能的有用性.
- 探索声乐特征 (蜂蜜谱图,MFCC) 与认知/精神病学措施之间的相关性.
主要方法:
- 收集了14名精神分裂症患者的语音样本.
- 使用梅尔谱图和梅尔频率塞普斯特拉尔系数 (MFCC) 提取的声音特征.
- 用积极和消极综合征量表 (PANSS) 评估精神症状,用Cognitrax评估认知功能.
主要成果:
- 在声乐特征和认知功能之间观察到显著的负相关性,特别是工作记忆和持续的注意力.
- 在声乐特征和PANSS分数之间没有发现直接相关性.
- 认知功能似乎调解了精神病症状和声乐特征之间的关系.
结论:
- 语音分析显示出作为评估精神分裂症认知障碍的非侵入性方法的希望.
- 建议对更大,更多样化的样本进行进一步的研究,以概括发现.
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